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1

Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics‐relevant chemicals

Eilstein, Joan, Grégoire, Sébastien, Fabre, Aurélie, Arbey, Eric, Géniès, Camille, Duplan, Hélène, Rothe, Helga, Ellison, Corie, Cubberley, Richard, Schepky, Andreas, Lange, Daniela, Klaric, Martina,

Journal:

Journal of Applied Toxicology

Year:

2020

Language:

english

File:

PDF, 572 KB

english, 2020

2

Ueber Verunreinigungen des sogenannten chemisch reinen Glycerins

Journal:

Archiv der Pharmazie

Year:

1868

Language:

german

File:

PDF, 100 KB

german, 1868

3

Human hemofiltrate as a source of circulating bioactive peptides: Determination of amino acids, peptides and proteins

Andreas G. Schepky, Klaus W. Bensch, Peter Schulz-Knappe, Wolf-Georg Forssmann

Journal:

Biomedical Chromatography

Year:

1994

Language:

english

File:

PDF, 441 KB

english, 1994

4

High-performance liquid chromatographic determination of sulfated peptides in human hemofiltrate using a radioactivity monitor

Andreas G. Schepky, Peter Schulz-Knappe, Wolf-Georg Forssmann

Journal:

Journal of Chromatography A

Year:

1995

Language:

english

File:

PDF, 514 KB

english, 1995

5

Lotus leaf extract and L-carnitine influence different processes during the adipocyte life cycle

Ralf Siegner, Stefan Heuser, Ursula Holtzmann, Jörn Söhle, Andreas Schepky, Thomas Raschke, Franz Stäb, Horst Wenck, Marc Winnefeld

Journal:

Nutrition & Metabolism

Year:

2010

Language:

english

File:

PDF, 611 KB

english, 2010

6

Das Trocknen von Tabletten

Gottfried Schepky

Journal:

Pharmazie in unserer Zeit

Year:

1974

Language:

german

File:

PDF, 4.54 MB

german, 1974

7

Über eine Kombination von Papierchromatographie und Ringofenmethode zur Untersuchung einiger toxikologisch interessanter organischer Stoffe

H. Weisz, G. Schepky

Journal:

Microchimica Acta

Year:

1965

Language:

german

File:

PDF, 682 KB

german, 1965

8

Vergleichende Mikrosublimation organischer Substanzen mit Hilfe der Kofler-Heizbank

H. Weisz, G. Schepky

Journal:

Microchimica Acta

Year:

1967

Language:

german

File:

PDF, 394 KB

german, 1967

9

Zum Nachweis funktioneller Gruppen unter Verwendung der Ringofenmethode

H. Weisz, G. Schepky

Journal:

Microchimica Acta

Year:

1965

Language:

german

File:

PDF, 485 KB

german, 1965

10

Simultaneous HPLC determination of metabolites of the inflammatory cascade

A. G. Schepky, R. Siegner, W. Diembeck

Journal:

Inflammation Research

Year:

1997

Language:

english

File:

PDF, 111 KB

english, 1997

11

Specific determination of tyrosine-phosphorylated proteins and peptides by differential iodination

Andreas G. Schepky, Gerold Meinhardt, Sabine Austermann, Knut Adermann, Peter Schulz-Knappe, Wolf-Georg Forssmann, Ralf Hass

Journal:

Journal of Chromatography A

Year:

1996

Language:

english

File:

PDF, 809 KB

english, 1996

12

Measurement of coherent and incoherent π0 photoproduction off the deuteron with tagged photons up to the Δ region

U. Siodlaczek, P. Achenbach, J. Ahrens, H.-J. Arends, R. Beck, R. Bilger, H. Clement, V. Hejny, M. Kotulla, B. Krusche, V. Kuhr, R. Leukel, V. Metag, R. Novotny, V. Olmos de León, F. Rambo, M. Schepki

Journal:

Nuclear Physics A

Year:

2000

Language:

english

File:

PDF, 315 KB

english, 2000

13

Influence of cleansing on stratum corneum tryptic enzyme in human skin

A. G. Schepky, U. Holtzmann, R. Siegner, S. Zirpins, R. Schmucker, H. Wenck, K. P. Wittern, S. S. Biel

Journal:

International Journal of Cosmetic Science

Year:

2004

Language:

english

File:

PDF, 184 KB

english, 2004

14

Identifying and characterizing chemical skin sensitizers without animal testing: Colipa’s research and method development program

P. Aeby, T. Ashikaga, S. Bessou-Touya, A. Schepky, F. Gerberick, P. Kern, M. Marrec-Fairley, G. Maxwell, J.-M. Ovigne, H. Sakaguchi, K. Reisinger, M. Tailhardat, S. Martinozzi-Teissier, P. Winkler

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 578 KB

english, 2010

15

In Vivo Degradation of Human Fibrinogen Aα: Detection of Cleavage Sites and Release of Antithrombotic Peptides

L. Standker, R. Sillard, K.W. Bensch, A. Ruf, M. Raida, P. Schulzknappe, A.G. Schepky, H. Patscheke, W.G. Forssmann

Journal:

Biochemical and Biophysical Research Communications

Year:

1995

File:

PDF, 391 KB

1995

16

Considerations on photochemical genotoxicity. II: Report of the 2009 International Workshop on Genotoxicity Testing Working Group

Anthony M. Lynch, Peggy J. Guzzie, Daniel Bauer, Elmar Gocke, Satoru Itoh, Abby Jacobs, Cyrille A.M. Krul, Andreas Schepky, Noriho Tanaka, Peter Kasper

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2011

Language:

english

File:

PDF, 367 KB

english, 2011

17

In vitro detection of contact allergens: Development of an optimized protocol using human peripheral blood monocyte-derived dendritic cells

Hendrik Reuter, Jochem Spieker, Silke Gerlach, Ursula Engels, Wolfgang Pape, Ludger Kolbe, Robert Schmucker, Horst Wenck, Walter Diembeck, Klaus-Peter Wittern, Kerstin Reisinger, Andreas G. Schepky

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 532 KB

english, 2011

18

The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: Results of a ring-study in five laboratories

Natsch Andreas, Bauch Caroline, Foertsch Leslie, Gerberick Frank, Norman Kimberly, Hilberer Allison, Inglis Heather, Landsiedel Robert, Onken Stefan, Reuter Hendrik, Schepky Andreas, Emter Roger

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 891 KB

english, 2011

19

The Colipa strategy for the development and evaluation of novel alternative methods for the identification of skin sensitizers

P. Aeby, T. Ashikaga, S. Bessou-Touya, A. Schepky, F. Gerberick, P. Kern, M. Marrec-Fairley, G. Maxwell, J.M. Ovigne, H. Sakaguchi, K. Reisinger, M. Tailhardat, S. Teissier, P. Winkler

Journal:

Toxicology Letters

Year:

2010

Language:

english

File:

PDF, 83 KB

english, 2010

20

A novel in vitro method for the detection and characterization of photosensitizers

N. Karschuk, Y. Tepe, S. Gerlach, W. Pape, H. Wenck, K. Wittern, A. Schepky, H. Reuter

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

21

In vitro detection of contact allergens: Development of an optimized protocol and performance of an international ring study using human peripheral blood monocyte derived dendritic cells

H. Reuter, J. Spieker, S. Gerlach, H. Wenck, W. Pape, K. Wittern, A. Schepky

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 78 KB

english, 2011

22

A new skin penetration system containing an automated toxicokinetic module

Daniela Gerstel, Nora Metke, Stefanie Mueller, Mehdi Akhiani, Claus-Dieter Wacker, Horst Wenck, Andreas Schepky

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 88 KB

english, 2012

23

Development of an in vitro sensitization assay based on monocyte-derived dendritic cells

Andreas Schepky, Jochem Spieker, Silke Gerlach, Ludger Kolbe, Walter Diembeck, Wolfgang Pape, Horst Wenck, Klaus-Peter Wittern, Hendrik Reuter

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

24

Development of an in vitro assay for the assessment of photosensitizers

Andreas Schepky, Yeliz Tepe, Nadine Karschuk, Jochem Spieker, Silke Gerlach, Horst Wenck, Robert Schmucker, Klaus-Peter Wittern, Hendrik Reuter

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

25

White Tea extract induces lipolytic activity and inhibits adipogenesis in human subcutaneous (pre)-adipocytes

Jörn Söhle, Anja Knott, Ursula Holtzmann, Ralf Siegner, Elke Grönniger, Andreas Schepky, Stefan Gallinat, Horst Wenck, Franz Stäb, Marc Winnefeld

Journal:

Nutrition & Metabolism

Year:

2009

Language:

english

File:

PDF, 676 KB

english, 2009

26

The Effect of Hygroscopic Formulation Ingredients on the Sorption Characteristics of Tablets

Fischer, Martina, Schepky, Gottfried

Journal:

Drug Development and Industrial Pharmacy

Year:

1995

Language:

english

File:

PDF, 829 KB

english, 1995

27

Variation of Composition of an Enteric Formulation Based on Kollicoat MAE 30 D

Flößer, A, Kolter, K., Reich, H.-B., Schepky, G.

Journal:

Drug Development and Industrial Pharmacy

Year:

2000

Language:

english

File:

PDF, 343 KB

english, 2000

28

Comparative Studies with Kollicoat MAE 30 D and Kollicoat MAE 30 DP in Aqueous Spray Dispersions and Enteric Coatings on Highly Swellable Caffeine Cores

Dangel, C., Schepky, G., Reich, H.-B., Kolter, K.

Journal:

Drug Development and Industrial Pharmacy

Year:

2000

Language:

english

File:

PDF, 886 KB

english, 2000

29

Preformulation the Role of Moisture in Solid Dosage Forms

Schepky, Gottfried

Journal:

Drug Development and Industrial Pharmacy

Year:

1989

Language:

english

File:

PDF, 1.36 MB

english, 1989

30

Genomic Allergen Rapid Detection In-House Validation--A Proof of Concept

Johansson, H., Rydnert, F., Kuhnl, J., Schepky, A., Borrebaeck, C., Lindstedt, M.

Journal:

Toxicological Sciences

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

31

Gluteal and abdominal subcutaneous adipose tissue depots as stroma cell source: gluteal cells display increased adipogenic and osteogenic differentiation potentials

Iwen, Karl Alexander, Priewe, Anna-Christin, Winnefeld, Marc, Rose, Christian, Siemers, Frank, Rohwedel, Jürgen, Cakiroglu, Figen, Lehnert, Hendrik, Schepky, Andreas, Klein, Johannes, Kramer, Jan

Journal:

Experimental Dermatology

Year:

2014

Language:

english

File:

PDF, 863 KB

english, 2014

32

Studies Comparing Kollicoat MAE 30 D with Commercial Cellulose Derivatives for Enteric Coating on Caffeine Cores

Scheiffele, Silke, Kolter, Karl, Schepky, Gottfried

Journal:

Drug Development and Industrial Pharmacy

Year:

1998

Language:

english

File:

PDF, 1.02 MB

english, 1998

33

Epigenetic Regulation of Depot-Specific Gene Expression in Adipose Tissue

Gehrke, Sandra, Brueckner, Bodo, Schepky, Andreas, Klein, Johannes, Iwen, Alexander, Bosch, Thomas C. G., Wenck, Horst, Winnefeld, Marc, Hagemann, Sabine, Kanzaki, Makoto

Journal:

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

34

Structure and function in proteins

Aoki, A., Pasolli, H.A., Raida, M., Meyer, M., Schulz-Knappe, P., Mostafavi, H., Schepky, A.G., Znottka, R., Elia, J., Hock, D., Beier, H.M., Forssmann, W.G.

Journal:

Molecular Human Reproduction

Year:

1996

Language:

english

File:

PDF, 771 KB

english, 1996

35

Studies on Modifying the Tackiness and Drug Release of Kollicoat® EMM 30 D Coatings

Erdmann, H., Gebert, S., Kolter, K., Schepky, G.

Journal:

Drug Development and Industrial Pharmacy

Year:

2003

Language:

english

File:

PDF, 783 KB

english, 2003

36

Comparison of protocols for measuring cosmetic ingredient distribution in human and pig skin

Gerstel, D., Jacques-Jamin, C., Schepky, A., Cubberley, R., Eilstein, J., Grégoire, S., Hewitt, N., Klaric, M., Rothe, H., Duplan, H.

Journal:

Toxicology in Vitro

Year:

2016

Language:

english

File:

PDF, 379 KB

english, 2016

37

Solubility of cosmetics ingredients in 6 different solvents and applicability to skin bioavailability assays

Rothe, H., Schepky, A., Hewitt, N., Cubberley, R., Duplan, H., Eilstein, J., Gerstel, D., Grégoire, S., Jacques-Jamin, C., Klaric, M.

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 67 KB

english, 2015

38

Cosmetics Europe skin bioavailability and metabolism project

Rothe, H., Cubberley, R., Duplan, H., Einstein, J., Gregoire, S., Jamin, C. Jacques, Klaric, M., Hewitt, N., Schepky, A.

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 68 KB

english, 2016

39

Comparison of protocols measuring diffusion and partition coefficients in the stratum corneum

Rothe, H., Obringer, C., Manwaring, J., Avci, C., Wargniez, W., Eilstein, J., Hewitt, N., Cubberley, R., Duplan, H., Lange, D., Jacques-Jamin, C., Klaric, M., Schepky, A., Grégoire, S.

Journal:

Journal of Applied Toxicology

Year:

2017

Language:

english

File:

PDF, 2.66 MB

english, 2017

40

Solvent Solubility Testing of Cosmetics-Relevant Chemicals: Methodology and Correlation of Water Solubility to In Silico Predictions

Grégoire, S., Cubberley, R., Duplan, H., Eilstein, J., Lange, D., Hewitt, N., Jacques-Jamin, C., Klaric, M., Rothe, H., Ellison, C., Vaillant, O., Schepky, A.

Journal:

Journal of Solution Chemistry

Year:

2017

Language:

english

File:

PDF, 523 KB

english, 2017

41

Photo-safety assessment for cosmetics based on in vitro tests

Pfannenbecker, Uwe, Wenck, Horst, Schepky, Andreas

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 92 KB

english, 2017

42

Impact of cutaneous bioavailability in local skin toxicity: Preliminary results from cosmetics Europe skin bioavailability and metabolism task force

Gregoire, Sebastien, Cubberley, Richard, Duplan, Helene, Eilstein, Joan, Ellison, Corie, Hewitt, Nicky, Jacques-Jamin, Carine, Lange, Daniela, Klaric, Martina, Rothe, Helga, Schepky, Andreas, Roe, Amy

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 85 KB

english, 2017

43

Better understanding of bioavailability of cosmetic ingredients: Results from Cosmetics Europe Skin Bioavailability project

Schepky, Andreas, Cubberley, Richard, Duplan, Helene, Eilstein, Joan, Ellison, Corie, Gregoire, Sebastien, Hewitt, Nicky, Jacques-Jamin, Carine, Lange, Daniela, Roe, Amy, Rothe, Helga, Klaric, Martina

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

44

Metastasierendes Lymphosarkom bei einer Riesenschlange, Eunectes murinus (Linnaeus, 1758)

Frank, Werner, Schepky, Arwid

Journal:

Pathologia veterinaria

Year:

1969

Language:

german

File:

PDF, 1.56 MB

german, 1969

45

A Novel In Vitro Method for the Detection and Characterization of Photosensitizers

Karschuk, Nadine, Tepe, Yeliz, Gerlach, Silke, Pape, Wolfgang, Wenck, Horst, Schmucker, Robert, Wittern, Klaus-Peter, Schepky, Andreas, Reuter, Hendrik, Schönbach, Christian

Journal:

Year:

2010

Language:

english

File:

PDF, 718 KB

english, 2010

46

Comparison of the metabolism of 10 chemicals in human and pig skin explants

Géniès, C., Jamin, E. L., Debrauwer, L., Zalko, D., Person, E. N., Eilstein, J., Grégoire, S., Schepky, A., Lange, D., Ellison, C., Roe, A., Salhi, S., Cubberley, R., Hewitt, N. J., Rothe, H., Klaric,

Journal:

Journal of Applied Toxicology

Year:

2018

Language:

english

File:

PDF, 748 KB

english, 2018

47

Cosmetic Europe's long range science strategy – A non-animal safety assessment case study for phenoxyethanol, a cosmetic ingredient

Nepelska, M., Cronin, M.T.D., Cubberley, R., Dent, M., Firman, J.W., Fisher, J., Kenna, G., Mahony, C., Nicol, B., Piechota, S., Przybylak, K., Schepky, A., Tozer, S., Troutman, J., Desprez, B.

Journal:

Toxicology Letters

Year:

2018

Language:

english

File:

PDF, 54 KB

english, 2018

48

Skin Doctor: Machine Learning Models for Skin Sensitization Prediction that Provide Estimates and Indicators of Prediction Reliability

Wilm, Anke, Stork, Conrad, Bauer, Christoph, Schepky, Andreas, Kühnl, Jochen, Kirchmair, Johannes

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 4.18 MB

english, 2019

49

Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database

Kluxen, Felix M., Grégoire, Sébastien, Schepky, Andreas, Hewitt, Nicky J., Klaric, Martina, Domoradzki, Jeanne Y., Felkers, Edgars, Fernandes, Joshua, Fisher, Philip, McEuen, Steven F., Parr-Dobrzansk

Journal:

Regulatory Toxicology and Pharmacology

Year:

2019

Language:

english

File:

PDF, 2.21 MB

english, 2019

50

Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database

Kluxen, Felix M., Grégoire, Sébastien, Schepky, Andreas, Hewitt, Nicky J., Klaric, Martina, Domoradzki, Jeanne Y., Felkers, Edgars, Fernandes, Joshua, Fisher, Philip, McEuen, Steven F., Parr-Dobrzansk

Journal:

Regulatory Toxicology and Pharmacology

Year:

2019

File:

PDF, 2.21 MB

2019